Northern America Top 1,000 Companies List by Market Cap in August 2026

Curaleaf Holdings is a Cannabis company. Curaleaf has a presence in 23 states, owns and operates 101 dispensaries, 23 cultivation sites, and 30 processing sites with a focus on highly populated, limited license states, including Arizona, Florida, Illinois, Massachusetts, New Jersey, New York, and Pennsylvania. The headquarters is in USA.

Ingevity is a Specialty Chemicals, High Performance Carbon Materials and Engineered Polymers company. It operates from 25 locations around the world and employs approximately 1,850 people. The company products are used in a variety of demanding applications including asphalt paving, oil exploration and production, agrochemicals, adhesives, lubricants, publication inks, coatings, elastomers, bioplastics and automotive components that reduce gasoline vapor emissions. The headquarters is in USA.

Rush Street Interactive is a developing, supplying and operating regulated Online Gaming company. The headquarters is in USA.

Portola Pharmaceuticals is a Biotechnology company. It is having more than 380 employees and has offices around the globe and serves patients in more than 50 countries. The company has developed and commercializes two approved complement inhibitors to treat patients with paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome (aHUS) as well as the first and only approved complement inhibitor to treat anti-acetylcholine receptor (AchR) antibody-positive generalized myasthenia gravis (gMG) and neuromyelitis optica spectrum disorder.

Trevi Therapeutics is a clinical-stage biopharmaceutical company that is developing the investigational therapy Haduvio™ to treat serious chronic cough conditions by targeting the central and peripheral nervous systems. Headquarters is in USA.