California Top Companies List by Market Cap as of August 2026

Software company related to real time monitoring systems. Headquarters is in California, USA. Trimble is transforming industries such as agriculture, construction, geospatial and transportation. Core technologies in positioning, modeling, connectivity and data analytics connect the digital and physical worlds to improve productivity, quality, safety, transparency and sustainability.
As on 2022, TRIMBLE has 11,825 employees
TRIMBLE annual revenue generated for period ending Dec-2022 was 3,676 million USD.

Prometheus Biosciences, Inc. is a biotechnology company focused on the precision approach is designed to transform the treatment of immune-mediated diseases starting with inflammatory bowel disease (IBD). The company annual revenue is 3 million USD and annual net loss of 90 million USD for year ending December 2021. The headquarters is in USA.

Merck acquired Prometheus Biosciences Inc. for 11 billion USD in the year 2022.

Costar Group provides real estate services like analytics and information related to commercial properties. Company headquarters is in USA. They combine research, technology, innovative tools and powerful marketing to connect the commercial real estate professionals with the data, insights, decision makers and leads to succeed.

As on 2022, Costar Group has 4,742 employees.

Semtech Corporation is a Mixed Signal Semiconductors company. It enabling mission critical applications for three of the industries fastest growing markets they are internet of things, data centers and mobility. The company balanced portfolio of semiconductor products is used by original equipment manufacturers and their suppliers for automotive, broadcast equipment, data centers, passive optical networks, industrial, Internet of Things, LCD TVs, smartphones, tablets, wearables and wireless infrastructure applications. The headquarters is in USA.

Biomarin Pharmaceutical is Pharmaceutical and Biotechnology Company with headquarters is in California, USA.

It develops innovate therapies and life-threatening rare diseases and medical conditions.It consists of seven commercial products for the treatment of various diseases.

As on 2022, Biomarin Pharmaceutical has 3,082 employees.

Biomarin Pharmaceutical annual revenue generated for period ending Dec-2022 was 2,096 million USD.

Penumbra is a Healthcare company. It designs, develops, manufactures and markets novel products and has a broad portfolio that addresses challenging medical conditions in markets with significant unmet need. The headquarters is in USA.

Align Technology is a global medical device company with headquarters is in California, USA. Align Technology reimagine and reinvent the way orthodontic and restorative treatment is presented and delivered to millions of people around the world.

As on 2021, Key metrics:

• Annual Net Revenues: 4.0 billion USD.
• Invisalign Patients: 13.4 millions.
• Active Patients: 1,459.

Ason 2022, Employees: 23,165

The Clorox Company (NYSE: CLX) is a leading multinational manufacturer and marketer of consumer and professional products. Headquarters is in USA.

As on 2022, The Clorox Company has 9,000 employees.

Exelixis is a Commercially successful and Oncology Focused Biotechnology company. The company established a broad drug discovery and development platform that has served as the foundation for continued efforts to bring new cancer therapies to patients in need. Headquarters is in USA.

DECKERS OUTDOOR CORPORATION is Footwear and Apparels producing and distributing company with headquarters is in California, USA.